Top definition
1.a notorious and obvious steriod user;
2.to pull a tweakle is wen its obvious sum kid used roids u yell tweakle and run, of course avoiding the possible beating that may be ahead;
3.if you use steriods you would call yourself a tweakler
1. fan 1: haha giambi is such a tweakle
fan 2: damn strait

2. TWEAKLE!... runn!

3. o yea, im a tweakler **flex**
by K-SO October 18, 2005
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