Top Definition
The shoes worn by meth heads, but the term could be broadened to include junkies or crackheads. Ugly, blocky, generic white shoes with tattered shoe laces that look like the tweaker barely even bothered to tie them. Tweaker sneakers are covered in dirt and various bodily fluids.
Get some new shoes you bummy lookin' motherfucker! Those kicks look like tweaker sneakers!
by money mike 305 November 06, 2009
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