Top Definition
Referring to a 'tweaker' or someone whom uses meth-amphetamines,when they clearly should not be...& Although the dope fiends have enough speed in their system to stay awake for two weeks,they are 'overamped' and incapable of speaking,moving, or performing the simplest task in a manner other than that befitting Frankenstein...
Dude's been up for 4 days on meth...Look at how slow and confused he is!!! Steer clear of him, he's officially turned into Tweakenstein!!!
by Murray St. James May 24, 2010

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