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15.
to be overly excited at a situation or event that is highly positive and causes exuberance beyond classification of excitement.
Scott won a vacation to Hawaii, a place he always wanted to go, causing him to call his friends and tweek.
by BT14 July 29, 2007
21 28
 
16.
Something or someone that is stupid, dumb, or crazy.
"Stop being such a tweek !"

Person#1: I failed the history test.
Person#2: That was so easy, you tweek !
by kimbop October 03, 2009
3 11
 
17.
something that looks strange or is very cool
dude that shit is tweek!
by steakman1 February 10, 2007
4 13
 
18.
To pinch or flick...

"I tweeked her nipple and she tweeked my clit with her tongue."
by Junebug December 14, 2005
18 30
 
19.
When a girl plays with her Vag for pleasure or to tease men
My hoe girl friend was caught tweekin off at a party, all the guy seen her cookie
by Savoyo August 03, 2008
12 28
 
20.
Can be a state of paranoia, Have to urge to hurt or kill somebody, Be Extremely mad (sometimes because of drugs or mental ilnesses)
Im going to Tweek on someone very shortly!

by Mike AKA TweeK February 06, 2007
6 23
 
21.
to enhance
"Dude, check out my tweeked up motorcycle..."
by kevsgrl2004 June 09, 2003
12 29