Top Definition
A positive movement and lifestyle. Often said when saying hello, or bye with the use of the hand gesture. Based off the clothing company "TUPO Clothing"

Stands for "Thumbs Up Pinkies Out"
Alright I'm going now guys later, *does gesture* TUPO
by tupo July 02, 2013
A person who has multiple personalities
That bitch is such a Tupo
by Mista_Waldo May 08, 2010
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