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When you've been driving too long and your ass starts to hurt real bad like a truck/semi driver's ass would.
Aw crap, I drove all the way to Vancouver and man, I got some serious trucker-butt.
by Derek M December 27, 2005
A practice used generally by college kids involving assaulting an unsuspecting victim (usually passed out) by placing your anus over the victim's nose.
I woke up this morning with a terrible hangover and a constant shit smell. I think I was trucker-butted last night.
by TBawler March 19, 2010