Top Definition
the pain one feels on the bottom of or just below their nose after wiping it too much with tissues. Usually occurs during alergy season or when he or she has a runny/congested nose
Damn, I hate allergy season. I'm always getting tissue burn after wiping my nose too much.
by UndeadMessenger May 26, 2007
when you wipe too much and your nose gets red and inflamed
Jeff: "Yo, I'm going to the store, you need anything?"
Jackie: "Ya, get my some Puffs Plus Lotion, I got mad tissue burn."
by Tina278 August 26, 2015
when you get a cold & use so many tissues that your nose becomes irritated & burned
Jeff: "Hey Julie Chen, I'm going to the store. Do you need anything?"
Julie Chen: "Ya, pick me up some Puffs Plus Lotion, I got mad tissue burn."
by Tina278 August 24, 2015
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