"Yo did you see Hilton duff Chino in the face"

"Chino is bleeding because he got duffed so hard"

"Some would should duff that kid, Chino, in the face"
by Douch B. September 28, 2007
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A brand of cool US Skate shoes.
Yo man, you see those dope Duff Roadrunners? Way Fresh!!
by PHIVOLCS March 24, 2004
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A different person, approachable,friendly , not defined by fashion and looks and takes little attention to their appearance. they really do not have to be fat and ugly, just different.
that duff makes me look so hot when we are together,her small booty makes mine look so big
by babylove_spongy June 3, 2015
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Dark brown or black cannabis remaining in a vaporizer bowl after vaporizing. The duff, which still contains some THC, is recycled rather than discarded by stingier enthusiasts.
Whoa, don't toss that duff, man! I'm saving that to make hash.
by John Woods August 25, 2008
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The leftover weed from a depleted vaporizer. It is often used to make canna-butter or sprinkled on food as an edible, since the the THC has been activated by the heat of the vaporizer.
Stoner 1: Damn, we’re out of weed!
Stoner 2: I got this duff , we could just eat some of that.

Stoner 1: Aw, hell yeah, let’s get blazed.
by teaoutdoors June 17, 2021
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The unattractive girl that a hot girl keeps around to make herself and her friends look better. Stands for "Dumb Ugly Fat Friend". THe DUFF tends to be a cockblock or a third wheel. See also "Grenade".
Why do I always get stuck with the DUFF?
by G. Sherman August 11, 2003
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