Top Definition
1) the state of dull/cracked talons with acute or chronic inflammation and potential lesions of ones talon or talons.

2) any state of sorrow, pain, discomfort, or general malaise in any part of the human body.
3) extremely hungover
I stayed up too late last night and drank five bud forties. Now my skull is throbbing, and I am at the library with a severe case of talonitis.
by kblaze83 July 22, 2010

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