Top Definition
Closely derived from the two words smegma and osmosis, smegmosis is the process by which bits of annoying crapola, not necessarily smegma in the classical dictionary sense, move mysteriously from one location to another.
Tom: How did this load of smegmatic smegmoids get on my desk? They used to be on Julie's desk.

Ed: Ahh, the mysterious process of smegmosis has occured.

Tom: Isn't that just smegmificent?
by Brandon De Graaf March 13, 2008

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