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1.
to gain carnal knowledge of someones friend or group of friends
james: so are you gonna get with debra?
todd: NO WAY! that girl smashed the homies
james: its cool man, i just got tested the other day and im still clean.
by irreverentalsharptongue May 01, 2009
 
2.
When a girl has had sexual relations with you OR more than one of your friends.
Yooo I heard you and Rachel did it.

friend: She a slut yo, she smashed the homies. She did me, Ron, Day Day, and that dude we sit next to in class. She get around like 2Pac in the 90's
by Big-Liek March 03, 2010