Top Definition
Apparently, it is an insult. May have originated in the film E.T. The Extra Testicle.

Greg:"Sinus Supremus!"

Elliot: "Zero charisma!"

E.T.: "Both fags, they are..."

Datarock: "Seen as supremus, you better know she's a genus!"

by Jvarna5 March 15, 2008

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