Top Definition
The ugliest sorority ever to exist.

EVER.
Holy shit! Did you see that whale?
What whale? oh! That's not a whale, that's a sigma iota sigma.
by argleblargle March 14, 2011
1 more definition
Some of the best people you will ever meet. Know how to party and have fun, but in a classy not trashy way. Everyone knows they are the best. Everyone wants to be a Sig I Sig!!
"Theres no family like a Sigma Iota Sigma family"
by xxx1234543 December 29, 2011

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