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To express astonished disbelief at what is being said (especially gossip).
Penny: Try thinking about this... Sheldon and Amy had sex!
Raj: Shut your ass!
by Spaz111 April 14, 2011
another form of "shut up", similar to "shut your mouth" or "shut your face."
- I won the lotto yesterday.
- Bullshit, shut your ass.
by KRHimself June 10, 2005