Meaning to shut your fucking mouth because you don't deserve to talk because your a fucking bitch that doesn't have a live because they keep talking like a ho.
Dude you should fucking SHUFFUP.
by Heebummie September 06, 2008
5 Words related to shuffup
I began to use Shup a while ago, without realising its a pretty old term. But at the same time (before I knew of the popularity of shup) I made I shuffup.

short for shut the fuck up. shu(t the)f(uck)up

-Ash
Guy1:you gotta press play...
Guy2:shuffup! I knew that!
by Ashley Buttle March 12, 2005

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