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2.
The act of being high with drugs of any sort, usually heroin. For example, you can get shot up or be shot up.
"I got shot up yesterday."
"I shot up last night."
by addictedtoheroinbishes February 28, 2010
 
1.
The act of using heroin interveniously.
I heard Joe was all shot up.
by stillalive September 13, 2007
 
3.
To be high because of drugs.
"Man, I'm so shot up!"
by Omnomnom1112 March 01, 2010
 
4.
When pimples look like little bullet wounds aka pimples are crazy
o shit you see dudes face it got shot up crazy
by P.O.P January 17, 2008