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1.
1) A extremely masculine, bitchy lesbian woman.

2) a mannish lesbian usually identified by an overwhelming ammount of facial hair and usually sporting a mullet

3) A really masculine lesbian
I thought that dude was hot, tillm I found out it was a sharpi

Her mom is a sharpi
by Noah Webster December 19, 2004
 
2.
a marker, derived from the name brand
Hey asshole get me a sharpi so i can mark this shit.
by matthew dufrene March 02, 2005