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When a vegetarian or vegan secretly indulges in meat, or when a meat-eater tries to lure a vegetarian/vegan into eating meat.
Lori shakes hands with beef every now and then.

Come on, Lori! (Holding a burger in her face) Shake hands with beef!
by Pink Dog June 07, 2006
The act of wanking it, jerking off, or masturbating as it is most commonly called.
Im gonna go shake hands with beef before we hit the road, I don't want to have to sperm it up on the way.
by Ginkyzord October 11, 2006