The anithesis of a ladies man; a true man's man; magically fagalicious
Fuck you serio.
by A homosexual May 7, 2004
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internet abbreviation for the word serious, usually used in combination with "r u" or "u canot be"
OMG WTF I AM SO SERIOS whine whine
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To have every sexually transmitted disease at once. It thus neutralizes the infected from the affects of the various diseases. However, whoever they have sex with will die instantly.
Jeff has Serio Syndrome. He fucked Deb last night and she immediately died.
by Ridwiz October 24, 2012
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the spelling of "serious" for retards

a word 9 yr olds fuck up
by J1my November 14, 2021
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A bad case of crazy, obsessive, temperamental, stalker-like qualities in a person who has the physical features of a soccer mom.
Dude, my ex has a really bad case of the serio
by JonnyTroll June 9, 2010
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Literal translation "serious fart"
It's equivalent in English is "real shit"
Serio Pedo, you don't have no salsa, but you're serving tacos? or
My car just broke down dude, serio pedo.
by Cheymez May 24, 2017
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