A abbreviated word for satisfied.
This weed is so so. I'm not saffo.

You saffo? Or should I pack another bowl.
by contron July 4, 2005
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First they was called "saffos" then lesbos...
by ou5thguy May 4, 2005
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A slang term for lesbian or "lesbo"
Those girls over there are a couple of saffos.
by _Facade October 22, 2020
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