Top Definition
s&e
a title used to designate that girl who is both short and easy (s&e), and sleeps with every and any guy that she sees, is extremely disgusting and has the most annoying voice anyone could possibly here, should normally is seen wearing a bag over her head
hey, did you here what happened to john last night?
yeah, i heard that s&e cornered him, sucks!
yea, his eyes will stink for weeks

i heard that an s&e was on the loose...someone get her mask!
by p.o.08 May 16, 2010

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