"the truth is, everyone is fucked up."
pertaining not exclusively to being intoxicated, but tired, unhappy, depressed, in-a-rut, anxious, a-regularly-nervous-person, a psychotic, etc....
drunk friend: "dooooode, imz so fucked up rightnow! what am i going to doooooo!!!??"
sober friend: "don't worry about it man, everybody's fucked up! rule 173."
A: "god dam it i'm sooo fucked! i didn't finish the English paper man!"
B: "it's alright, we're all fucked anyway!"