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1.
1. A thought or expression used when you have an expectation that is crushed beyond misery.
2. Extreme disappointment.
3. Complete shock or surprise.

Related to strongbag/strong bad.
Guy spots really hot girl and decided to go for it. On his way he imagines how the score would be and thinks he has it locked in.

Guy: Hey good looking.
Girl: Get away, pig.
Guy to himself: --Right in the Face!--
by Yoyoma February 23, 2004