Top Definition
a disaster, something that goes wrong, failure in general. Stems from the fact DNA of retarded people is a genetic train wreck.
Guy 1: Man, my car got wrecked yesterday
Guy 2: That's total retard DNA, man.
by TheVoiceOfReason May 02, 2006

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from daily@urbandictionary.com. We'll never spam you.

×