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A popular recreational drug of the 60s and 70s. Quaaludes (Methaqualone) are a group of CNS depressants classed as "hypnotic sedatives" with a similar effect to alcohol. Effects are sedation, decrease in anxiety, loosening of inhibitions, and loss of balance. Some people experience pleasant body effects. Side effects include disorientation, extreme sedation/sleep, grogginess the next day, and memory loss. One should be careful not to combine quaaludes or benzodiazepines with alcohol or other CNS depressants (opiates, ghb, etc). They are synergistic drugs and can greatly amplify the effects and side effects of each drug, and cause extreme illnes and possibly death. The manufacture of quaaludes was ceased in the early 80s due to drug abuse.
Doctors used to prescribe qualudes for anxiety.
by Jessica Stanley July 01, 2006

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Tranquilizer, drug, date rape, mickey finns. Pills to slip in a persons drink in order to take advantage of them sexually or other wise.
'I feel fucked, i think someones spiked me with a Qualude'
by LukeyGee May 03, 2006

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a very kick ass tranquilizer
Dude, i stole these qualudes from the vet
by Buddy March 09, 2005

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A drink served at a bar called the "cafe" in Macomb, IL, home of Western Illinois University. The drink contains 9-10oz of top-shelf hard alcohol and 1-2oz or half and half. It will get you fucked up. It cost $5 on wednesdays and around $10 every other day.

Greatest drink on campus!
I got fucked up from a qualude last night at the cafe
by Vick Macki May 15, 2009

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