Top Definition
a chronic condition in which a man's behavior makes it seem as if he has a pussy between his legs.
Ray just let his girlfriend cancel our bowling night, his pussitis must be acting up again.
by pantew April 26, 2006
the state of having an inflamed puss puss
Wow girl, my pussitis is killing me, it is really red and hurts.
by The dirty lihn January 30, 2011
an imaginary illness that explains why a girl is crabby or otherwise unhappy for no good reason.
Tori: What's up with Sharon? She's a super bitch today!
Alice: Oh it's just her pussitis acting up again.
Tori: Wow she has that a lot!!
by renee151 May 18, 2008

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