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The act of hurting or some one that’s hurt
Guy 1 : I had that guy profen when I smacked him with my meat

guy 2: I hate when I get profened
Profen by Sethsapussy March 25, 2022
“Mad chicks have been on my shit lately I be profen
Profen by morandick April 14, 2025
Person A: “Hey read this
Person B: “Ibuprofen”
Person A: “You be what?”
Profen by omnizaki April 7, 2026
VERB: /pröfən/ to masterbate, goon, jerk meat, jack off, Jill off, beat box, shuck corn, pop off, or jork it. Often used in the context of aggressive or habitual action. Etymological Orgin: Irresponsible genie wish.
A: "Look! Ibuprofen!"

B: "yo? You be PROFEN???"
Profen by Anonymous_platypus October 7, 2025
Profen means to masturbate
You be profen all night huh?
Profen by mangoasechurcknorris October 8, 2025