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1.
administering the drug extasy, (MDMA), rectally. The more the capillary exposure, the higher you get
I like to swallow my pills, Jason likes plugging his. He says he gets higher that way.
by anonymous August 26, 2003
211 68
 
2.
A very effective way of doing most drugs. Basically, you stick it up your butt.

There's a stigma against it because a lot of people are scared of their own rectums. Ultimately, it's a matter of personal preference; if you're adventurous, try it- it works great. If not, there's plenty of other methods that don't make you feel violated.
I plugged Adderall just before I wrote this definition. And IMO, plugging turns a good high into a GREAT high.

You can plug pretty much anything except weed and DXM- but always Google it first, just in case.
by relates30598340503498 August 12, 2010
66 22
 
3.
The anal administration of any drug. Most commonly done with MDMA, DMT, or 2cb
Plugging DMT is an effective way to skirt using an MAOI to achieve an ayahuasca like high which is less intense but much longer lived than vaporizing it.
by Rimjob Jesus February 03, 2010
28 21
 
4.
when a girl is menstruating and acting kinda bitchy, like she's pms or worse; also if her face is broken out when it is not normally
Damn, what's up with Deb this morning? She must be plugging.

Shit, my face is broken out for my big hook up with Alan. I hope he knows I'm plugging.
by spiderbesideher September 20, 2009
50 62
 
5.
when a girl puts on a strap on and does a guy in the ass.....yum yuum
j was plugging m last night
by Heidi-Fan April 22, 2010
14 41
 
6.
The act of drilling a 1 and a half inch hole in a womans back, and proceding to fuck her in that hole.
'Man, I plugged my girlfriend two nights ago, and she's still asleep...'

OR

'Plugging my girlfriend was so amazing last night, I just went to her viewing.'
by MrCheeseKeeper November 04, 2011
17 49
 
7.
when you stick your balls up someones arse hole
is jamie plugging rich??
by andy jims June 27, 2006
20 88