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4.
Slang for the perscription drugs Percocet or Percodan, which is an opiate or painkiller, commonly used recreationally for its euphoric effect.
Ironically, Percocet is an opiate, which is a nervous system depressant, and the slang term perc cannot be verbally distinguished from perk, which means to make more alert or active.
I just popped a couple percs my doctor gave me for my back pain.

His dealer said percs were going for $1.50 a pill.
by A Clockwork Orange October 24, 2006
 
1.
Street name for the prescription painkiller Percocet. Generically known as Oxycodone.
Man, I love the way those percs fuck me up. I just took five more tablets.
by Brandon B. October 01, 2003
 
2.
short for "percolator" (I could be spelling that wrong). A perc is an additional chamber in a bong, and its purpose is to make the hit more smooth. Bongs can have multiple percs.
Jimmy-Jimmy just bought a rare discontinued triple-perc RooR bong over at his local headshop for $400. It fucking rips.
by Spaceman Spliff June 09, 2007
 
3.
short for the narcotic perscription drug percoset or any one of its forms such as oxycodone or oxycontin; makes you feel warm, happy, and relaxed. highly addictive, people not only swallow the pill but take it orally crushed (for a faster reaction) or snort it.
I'm percin', dude, I'm feeling no pain.
by Xeokym December 30, 2004
 
5.
Vocal percussion (beatboxing) in an a cappella group
That guy's perc is so good!

Who percs for the Pentatonix?
by acappellagurl November 17, 2013
 
6.
Allsome, extraordinary, amazing, cool, priceless
When FewnwayKing was told that Emma Watson admired his allsome white hoodie, he exclaimed: "Yo!! Emma loves me! This is totalllly percs!"
by michland November 08, 2011
 
7.
Slang for the drug percocet
He just popped a perc
by quavo October 03, 2014