Top Definition
Generally, the disappearance from one's regular social activities and friends due to the effect of a new penis in one's life. Usually a temporary condition, usually complained about by friends when one finally resurfaces. Not to be confused with poonpoof.
Heffer, because you went all peenpoof on me I had to find someone else to go to the club with last weekend... not cool!
by OaklandSweety July 12, 2010

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