Pills prescribed by physicians to patients who are in an uncomfortable amount of pain and are in need of relief. Popular pain killers include hydrocodone, oxycodone, acetaminophen (Tylenol) and codeine.

When taken in a non-medical way, more than prescribed for example, users can get a 'high' feeling without having to smoke anything :). aka poppin' pills
Billy: dude, you high?
Jimmy: yeahhhhh man i just popped some pain killers before school... i'm all wooozy and tingly n shit its awesome!
by pill-popper944 May 25, 2010
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by Wathg9 April 7, 2022
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