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1.
Something or someone who is constantly causing trouble. Derives from the TV series "Stargate SG1" in which a bounty hunter is describing Colnel O'neill (see example).

Usually said in situations where (english) profanity is forbidden.
Aris Bok, "And you O'neill, you're just a pain in the mik'da."
O'neill (question to Te'alk), "Neck?"
Te'alk, "No."

Me talking to my frozen computer, "Damn, what a pain in the mik'da!"
by vordmeister August 29, 2010