When one commits a "hit and run" but ends up exposing themselves with evidence left behind or hurting themselves by doing something crazy or erratic and ends up running away.
Example 1:
Kelly: Hey Haley! Did you see the hit and run on the news last night?
Haley: Yeah, turned out to be an oof and run when he left his license plate behind.

Example 2:
Emery: I am going to tell Serena I like her.
Charlene: You know that could lead to a big oof and run if she doesn't like you back.
by CrownedMcUnicorn June 23, 2019
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A nigga that's oofing around like a roblox player
Why u so nigga oof ae aeeeeeeeeeee for uuuuuuu
by Nigga oof ae June 1, 2018
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An earth-shattering screech containing the letters o and f. Commonly used while gaming.
If you lose this game im level 5 oofing you Jonathan!!
by May 18, 2022
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To make someone feel better/ To make the situation better
I thought I'd make a joke to ease the oof that was going on.
by Amaya Ayaka July 2, 2020
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The most extreme form of "oof" to ever exist. Is commonly said when someone has been in a state of extreme discomfort.
"My house burnt down"
"GIANT OOF"
by TOP NOT BOTTOM April 25, 2019
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