When an fat dumpy lesbian beats herself off and since she's so fat she aggressively rubs her knuckles on her puss to get off
Patti couldn't get the job done with her dildo so she ended up knuckling one off on that big fat pussy
by Bigdickballer420 July 24, 2017
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1. To quickly squeeze out a shit
2. To pinch off the end of a rather large shit in order to be done quicker.
Jerry had to pinch one off as the game started in ten minutes.
by Anonymous April 12, 2003
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to masturbate;

the circular motion (like a piston) of one who is furiously beating his meat.
sometimes, when I see your mom, I go home and spin one off
by droolbomber August 20, 2010
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Did you hear Nic Pledged a Fraternity?

Yaa now he sleeps and showers with 50 guys in the same room. He said he has to go into the bathroom to Knuckle one off!
by Mr Shocker September 9, 2009
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To pleasure oneself; a synonym for masturbate.

See also: wordwank/word
"Man, I peeled one off last night after watching that hot porno"
by Rafe May 16, 2003
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It is, indeed, yet another euphemism for masturbation.

As the description suggests, it generally refers to male masturbation.
I spent half the day, at work, in a cubicle in the toilets; fantasizing about rough sex with my boss, while having one off the wrist. Eventually I had to move to another cubicle when the toilet roll ran out.
by Jimi p August 11, 2006
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