The term is used to say a person, most usually a male, is crazy in love or lust over a girl, will focus total attention on her, ignoring his friends; maybe a hint that she is exploiting him.
i never see him now that he's smitten with his new girlfriend. he'll do anything for her; she's got his nose wide open.
by roxanne questi August 22, 2013
1 more definition
It means like a dog in heat, a guy can smell that the female is in heat. He has the hots for you!
All that nasty stuff girl does for him, got his "nose wide open"
by Ol Gurl March 18, 2009