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NoFriendsDiseaseItis 

The disease of the lonely and pathetic, characterized by a marked lack of any sort of friends. It is speculated that not even the mother of one with this condition even cares for him or her, and there is no known cure nor will there ever be one.
"Why does this guy keep trying to hang with us all the time? He's like a satellite..."

"Oh, he's got no friends. Must be nofriendsdiseaseitis."
NoFriendsDiseaseItis by Daem0n February 10, 2009

neufriend 

The gender-neutral term for a significant other (as opposed to "boyfriend" or "girlfriend")
omg, Julian, your neufriend is such a hot mess.
neufriend by 4n4lslut June 22, 2015
a nick name for the nintendo game system that pretty much speaks for itself. constant video gaming + no friends
What you going to play nofriendo all night long or are you going out.
nofriendo by chillcat May 30, 2003
Slang used for a gamer that does nothing but play video games his whole life.
Fuck that kid, let him go play his Nofriendo
Nofriendo by Brian Ming September 17, 2005
No friends as the direct result of playing too many video games.
He just sits around playing Nofriendo all day.

Too much nintendo leads to Nofriendo.
Nofriendo by ninjet June 11, 2006

nofriends 

having or possessing no friends or companions due to excessive or chronic faggotness.
"lookit that nofriends"
nofriends by buckleylovesrobbie February 3, 2010