Top Definition
the best girl on the planet. she is the most caring, loveable happy, crazy, sexy, beastiest person ever.
dude1: hey man you see that hot ass chick over there?

dude2: ya man she's such a nadene.
by mad kilg gaurd September 29, 2011
Alcohol, your friend
Dude, i FUCKED Nadene so hard last night. (you got trashed)
Lucky, we only made out. (a buzz)'
I'm hanging out with Nadene this weekend!
by ANDIEEE October 15, 2006
Elderly hermaphrodite from "Hoarders" that is extremely frightening and menacing, as well as stubborn, and lives in a trailer because her house is so disgusting. Her husband, a fat lazy disgusting redneck, is depressed over the house, but too lazy to do anything, so one can easily be sympathetic towards his plight.
Nadene's Husband: Can you get me a pickle?
Nadene: (growling voice) I CAN'T GET YOU A PIIICCCKKKKLLE! I'm in a pickle! (To Heather, the woman trying to help them) You're full of *beeeeep* Heather!
Heather: (Spazzing and yelling and having a fit on the street, obviously frustrated) GGGGRRRRRAAAARRRRR!!!!!
by HoarderDef August 31, 2011
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