Top Definition
The effect experienced by any man when confronted by a naked chick whilst holding a video camera.

Symptoms include heavy breathing, excessive talking, telling blatantly unfunny jokes, and generally acting like a complete muppet.
I found some really good home-made porn a while back but the guy had terrible muppet syndrome. I wish that guy would just shut the fuck up.
by The Other Greg June 13, 2006
8 Words related to muppet syndrome

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