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1.
Another word for an act of folly. May happen after consuming mass quantities of alcohol, or simply by having defective genes.
Brian Shimek has regular misadventures that involve rooftops, manginas, and trips to the ER.
by Braxtron May 06, 2003
 
2.
mishap or misfortune; fiasco
There were a series of misadventures that followed, after being diagnosed with tay sachs.
by shogun daniel September 14, 2008