Top Definition
The headach one gets from working with someone named Mike.
A: Dude, you look like you're in agony. What's up?
B: I've got a "Mikegrain headache" man. Worst ever. There's a project due next week and he's freaking out like it was due yesterday.
by Bryan Gilbreath August 28, 2009
10 Words related to mikegrain headache

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