Top Definition
Short for mescaline.
Three buttons of mesc.
by Bob Dole March 26, 2003
mescaline, a hallucinogenic drug
He was caught getting high off of the mesc that he stole.
by The Return of Light Joker August 07, 2008
Mad Elbow Skills Crew.
A group of people that specialize in playing four square with their joints, especially the elbow.
The MESC was founded around June, in 2003
Hey you guys, i was just approved to be in the MESC! w00t
by Giga Byte September 10, 2005

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