Top Definition
1. hormones that exist in the brain of a human male that are released when something happens that only (heterosexual) males enjoy, often resulting in primal roaring and fist pumping
i.e. witnessing (or delivering) a huge tackle during a game of (American) football, or beating someone in a video game

2. hormones that must be stimulated to unlock menergy
Dude 1: RARRR! Who's your f*ckin' daddy?

Dude 2: Your mendorphins are out of control man, it's only Gears(of War)
by Cutris Franks August 24, 2008
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