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1.
Slang for San Mateo.
White boy1: Yo where you from kid?
White boy2: Matioooooo!
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Words related to matio:

san mateo bay area frisco san francisco san ho
 
2.
1. someone known to have chronic dandruff
2. a person who flakes consistently
"He bailed again?? What a Matio!"
by dandruff destroyer October 11, 2004
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