Mano is the latin word for Hand. A common saying "mano y mano" is Spanish for Hand to hand. Usually associated in engaging in throwing fisticuffs with two or more people, usually two. Keeping that definition in mind, a Manojob simply is a slang term for Handjob.
We didn't go all the way but I gave my boyfriend a manojob.
by Jake Ryan January 15, 2008