Mandrome (man syndrome): Can be one of two things (1) husband/boyfriend/any man really, "acts" like the total good guy around other people.....some might say; lucky to be associated with such a good guy; but then once at home with the wife and children (and/or any family), the true colors come out.....lazy, difficult,argumentative,smelly and gross. OR (2) Both in public and at home seems to have tourettes of the mouth.
by Everyday Woman's Woman March 27, 2009
Get the mandromemug. A beautiful intelligent woman, who continuously goes back to the same stupid asshole, over and over; thinking, this time, it's gonna be different.
That bitch done broke up and got back together with him so many times, she's got that Downs Mandrome. For real!!!!!
by KaJen August 21, 2015
Get the downs mandromemug.