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1.
A Quaalude (a tranquilizer, downer), or an abbreviation for a Honda Prelude (but only by the younger generation). Contrary to the belief of some idiots, it is not the word for crass behavior. That would be LEWD, you tools.
He took a bunch of ludes, amazed us all by his lewd behavior, and promptly passed out in the back of his buddy's Lude.
by Mr. Green Jeans September 02, 2005
517 123
 
2.
Abbreviation for the pharmeceutical named Quaalude. It was used in the 1960s and 1970s as an anxiolytic, for the treatment of insomnia, and as a sedative. It became highly popular for recreational use in the 1980's, particularly in California. The active ingredient is Methaqualone, a depressant which is now a schedule 1 substance in the United States. It is still available for prescription in Canada.
"Hey man you alright?"
"Yeah just a little on edge."
"Wanna lude?"

"Hey man sorry I was so out of it last night, someone slipped me a bad lude."
by jimjim November 26, 2005
279 81
 
3.
1 - Slang term for the drug methaqualude or simple quaaludes, a barbituate like Central Nervous depressant drug which causes clumsiness and fatigue, often used to treat insomnia and anxiety.

2 - "TO BE ON LUDES": Idiotical, Dull Minded, Dim-Witted, Stupid, Lacking intelligence, Feeble Minded.
1 - My doc recommended i take ludes for my insomnia, there illegal but TS.

2 - WTF?? Are you on ludes mate? dont you know what im getting at? you cant even follow the simplist of instructions cant you?
by Brother Number One July 24, 2005
148 67
 
4.
its a tranq from long ago
"ludes man FUCKING ludes!!! call up the ludes dude dude and get some fucking ludes"
by Tarryn November 27, 2004
107 65
 
5.
Quaalude
Chill out and take a lude
by Cobra March 14, 2003
114 75
 
6.
Vitamin Q, Quakers, Quas, Q's, Disco Biscuits, Mandies,
Lemmons, Wallbangers, Quacks. Real name Methaqualone. A drug synthesized back in 1951 in India by two men named Indra Kishore and Hussain Zaheer. Was commonly used at clubs back in the 60's and 70's at discos (hence the name "Disco Biscuits") to make you feel better while you danced and partied. There were also special bars where they would serve non alcoholic beverages to cater to the people who used it. Now in decline due to it being declared a Schedule 1 substance.
Ludes used to be the one and only college past time.
by Matt the stud June 17, 2010
26 12
 
7.
Vitamin Q, Quakers, Quas, Q's, Disco Biscuits, Mandies,
Lemmons, Wallbangers, Quacks. Real name Methaqualone. A drug synthesized back in 1951 in India by two men named Indra Kishore and Hussain Zaheer. Was commonly used at clubs back in the 60's and 70's at discos (hence the name "Disco Biscuits") to make you feel better while you danced and partied. There were also special bars where they would serve non alcoholic beverages to cater to the people who used it. Now in decline due to it being declared a Schedule 1 substance.
Ludes used to be the one and only college past time.
by jkiller212 June 09, 2010
32 25