Lopo 

Means Laughing Our Pants Off.

Someone says something funny so you say lopo

Lopo by Tess Rhianna Griffith March 8, 2010

LOPO 

A nickname for the police in Lake Oswego, Oregon who do nothing but bust parties and write tickets for people who are 1 MPH above the speed limit, especially on Country Club Road.

Person 1: Why so sad?
Person 2: The fuckin' LOPO gave me a ticket when I was on Country Club the other day, I don't even think I was breaking the speed limit.
Person 1: Man, fuck the LOPO!

LOPO by mikewho50 March 24, 2010

Lopo 

someone who is irreverent

Dam, that guy is a lopo.

Lopo by Tom =D March 13, 2022

Lopo 

Lopo is an Italian man who has multiple personality disorder. Lopo can at times be mentally unstable with aggressive tendencies. Other times, he is a harmless gentleman. His personality changes are usually unpredictable.

“Look out! Lopo’s crazy side is back!”

Lopo by Sminchy August 28, 2022

LOPO 

To have LOw POtential in regards to career development. Such a feat is acheived by any (or all) of the following: extended luches, lack of focus, tiredness/sleeping on the job, speaking in code to mask inappropriate dialogue, being overweight or moving to DeKalb.

Rather than taking a call, LOPO puts his feet on the desk and eats more of his lunch.

LOPO by Kirk Gregory April 10, 2006

Lopo 

An insult used against anyone that is quite harmful meaning any of the following words, dumb, stupid, idiot, virgin, gay, asshole, dickhead, annoying, trout} or {mouth breather and more very rude words.

Guy 1: "That dude is so dumb!"
Guy 2: "Yea he's so Lopo"

Girl 1: "That dude is so annoying!"
Girl 2: "Yea he's such a Lopo"

Lopo by Lopo100 March 29, 2020

Lopo 

fat ass
hotty cunt

lopo is a fatass guy

Lopo by barocaro January 14, 2020