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1.
To let your frustratoins, anger, etc. go and not let it stress you out like it has been doing. Letting go means you don't have to stress over whatever you're letting go anymore.

The feelings tied with what you're letting go may still hold a place in your heart, but it is better to let whatever it is go and get on with your life than to let it hold you down and depressed.
They let each other go because they knew it wouldn't do any good staying together. It was a mutual break up.

They've moved on and are living happier lives now. I'm sure they're both happy they let go that stressful relationship.

*...and they lived happily ever after. fin*
by reb0und October 02, 2009
 
2.
The title of Canadian singer Avril Lavigne's debut album in 2002. One of the most successful debut albums in history. The album has sold over 17 million copies worldwide to this day. Lead singles were "Complicated," "Sk8er Boi," and "I'm With You." The album went on to win, if not nominated, for many awards.
Let Go is arguably Avril Lavigne's best album
by pizzaman88888 March 23, 2013
 
3.
someone particularly ,a guy hurts you really bad making you cry ,confused and questioning if you good enough for him just because he left you for some cheapsluttytrick. finding out that he's not worth your time so you
1.cry it all out
2. stop checking his myspace and comments
3.don't call him anymore
4.look back at all your memories, hugging, dancing,laughing
5.start to flirt hun (: hhahahah
Nick hurt her really, really bad ,and she's starting to let go
by homie gee December 16, 2008
 
4.
Imperative used by self-help books and therapists who tend to use copious amounts of cliches.
Obi-wan: Let go! Let go of your feelings.
by usetheforce January 16, 2010
 
5.
To reach orgasm.
Baby when you let go, you tossed your load all over my face!
by Big Bubber July 25, 2010
 
6.
let go of me, Gosh, leave me alone
undernath the world alone
by dan anderson November 30, 2004