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A combination of the words 'kryptonite' and 'testicle.' The one impenatrable force (most likely - but not exclusive to - a woman)that serves as the downfall of any man's well-being. Kryptonite : Superman :: Kryptesticle : Average man.
Meredith Grey is George's kryptesticle in Grey's Anatomy. Olive Oil is Popeye's kryptesticle. Heroin is a drug addict's kryptesticle. A nice pair of breasts can be considered a kryptesticle to a weak-willed man.
by Katie Bartels & Erin Dillon November 04, 2006

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