Top Definition
A big shitty cold sore, that takes away ones kiss-ability for two weeks, in effect preventing you from going out, or from picking up a girl (or guy) during that time.
That kiss-blocker on her mouth looks horrible. She won't be making out tonight.

Jackass had just sorted his pickup-lines, when he noticed Melanie's kiss-blocker.
Without missing a beat, he eyed up Melanie's cute ass friend.
by Rifwalker July 11, 2010

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